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The consensus also points out that the median Hcy for adults in China is in the range of 1314 umol/L, exceeding the diagnostic standard by more than 30% ( 2 Source and metabolism of Hcy Hcy is a product of demethylation during the methionine cycle, which is the only source of Hcy

The downstream pathway of Nrf2, on the other hand, involves inhibitory effects on oxidative stress, inflammation and apoptosis, including but not limited to several important protein molecules, such as HO-1, SOD, MDA, TNF-, ILs, the caspase family of proteins, Bcl-2 and Bax

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doi: 10.1016/j.jacc.2021.03.293 67

33,34 Other nutritional medical approaches to hypertension management include increased consumption of lycopene, mainly from tomato and watermelon, 35 cocoa, 36 and garlic, discussed here