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SKU: 50137550792
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In contrast, a prospective, randomized clinical trial of 80 patients with advanced HCC treated with sorafenib plus metformin or sorafenib alone revealed that adding metformin to sorafenib did not improve treatment efficacy in patients with HCC [224]

The cells were treated with different intensities of US (0 ~ 1.4 W/cm 2 ) and 15 M of the Ce6-equivalent concentration

relative AMPK activity of AMPK complex with different AMPK1 mutants when used SAMStide as substrate and reaction with AMPK inhibitor compound C was used as a negative control (n = 3 biological independent samples)