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Two trials in acutely hospitalized patients have shown that short-term (around 7 days) vitamin C supplementation increased concentrations of ascorbic acid in plasma and leukocytes and led to 34-35% improvements in mood state, as measured by POMS (142, 143)

Calcium is a mineral essential for healthy bones and is also important for muscle contraction,

Pharmacokinetic studies in rodents have documented rapid absorption following subcutaneous injection (Tmax approximately 30 minutes), with distribution to multiple tissues including liver, kidney, skin, and lung

doi: 10.1111/j.1440-1746.2010.06257.x, 16

It is featured by a decrease in Lactobacilli and an elevation in other bacteria typically associated with BV (Pramanick et al., 2019)