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Fosgonimeton (ATH-1017) is a structurally distinct small-molecule prodrug developed by Athira Pharma as a positive modulator of HGF/c-Met signaling the same mechanism class as Dihexa, but a different molecule

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Common positive reports include feeling more energetic during the day, subjectively better exercise performance, and a perception of "losing more fat and less muscle" compared to plain tirzepatide

They found at three weeks there was a better effect with the corticosteroid group compared to the Hyaluronan and placebo but by 26 weeks there was no difference between Hyaluronan, placebo or corticosteroids