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[DOI] [PMC free article] [PubMed] [Google Scholar] 224.Xue B., Huang J., Zhang H., Li B., Xu M., Zhang Y., Xie M., Li X

10.1016/0005-2728(96)00022-9 24 HirschhornT.StockwellB

Cholesterol biosynthesis and uptake in developing neurons

These molecules act as DAMPs that activate immune responses, including the STING (stimulator of interferon genes) pathway in microglia, promoting an acute inflammatory phenotype and the release of pro-inflammatory cytokines such as TNF- and IL-1