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Different carbon precursors can be used and the experimental setup can be modified for better performance

10.2217/fca-2019-0016 Pubmed Abstract CrossRef Google Scholar View reference in article 9

Hormonal Influence Hormonal changes during pregnancy, thyroid disorders, PCOS, or the use of oral contraceptives can activate melanocytes, leading to melasma and hormonal pigmentation

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Propionate biosynthesis occurs via three distinct routes: Bacteroidetes species preferentially employ the succinate pathway (Reichardt et al., 2014), while Firmicutes utilize acrylate and propanediol pathways, particularly when metabolizing pentoses/hexoses (Macfarlane and Macfarlane, 2003)