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Ubiquinone is a lipophilic free radical scavenger

The activity of ion channels is tightly regulated by transmembrane ion gradients, and even modest fluctuations in extracellular ion concentrations can markedly affect neuronal excitability and synaptic transmission and integration

Even though no final conclusions can be drawn, it became more and more evident that besides nutrients acting as down-regulators of tight junctions or as histone deacetylase (HDAC) inhibitors, also viral infections, toxins, hypoperfusion of the gut play a role (Table 7)

Neither cyanoB-12 nor methylB-12 have the properties of hydroxyB-12 as far as detoxification and redox control and cyanoB-12 cannot be used at high dose as it carries cyanide