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Fatty acids need to be activated before they enter the mitochondria for oxidation, which involves four enzymes, which are acyl-CoA dehydrogenase in the mitochondria or acyl-CoA oxidase in peroxisomes, enoyl-CoA hydratase, 3-hydroxylacyl-CoA dehydrogenase, and 3-ketoacyl-CoA thiolase [21]

BAT increased the AR nuclear-to-cytoplasmic ratio in most patients (Figure 4A), but to a notably greater degree in responders (Figure 4B)

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3.4 Modulation of metabolism-epigenetic axis Recent research has revealed that alterations in metabolic status can coordinate the function of immune cells by influencing epigenetic changes

others reduce systemic inflammatory metabolites via the gut