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We demonstrated that inhibition of autophagy worsened the senescence phenotype of vitiligo melanocytes, as revealed by an increased expression and nuclear translocation of p53, a higher expression of its target gene GADD45 and by elevated levels of p21 and p16

Molecular analyses reveal that 5-amino-1MQ administration alters expression of key genes involved in epithelial-mesenchymal transition, including increased ZEB1 and SIRT1 expression alongside decreased TWIST and SERPIN1 levels

IBD is one of the most common underlying causes of cobalamin deficiency in adult dogs

Fructose, Uric Acid