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No, taking Vitamin B12 supplements during chemotherapy can be risky

Temporary Bloating Though rare, some individuals experience slight bloating or digestive discomfort, which may be related to its immune-modulating and anti-inflammatory properties

Disulfiram does not reduce cravings, but instead deters drinking by making it physically unpleasant

With those caveats in mind, here's what the published data shows at each stage

Other B Complex Side Effects and When to See a Doctor Outside of stool changes, you may experience other side effects when taking B complex supplements, including: Diarrhea Facial redness Extreme tiredness Headache Nausea Upset stomach Bright yellow pee However, unless these are persistent or interfere with daily life, you may not need to see a healthcare professional if you experience these effects