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Eje serotoninrgico-dopaminrgico : BPC-157 modula sistemas centrales 5-HT y dopamina, particularmente en hipocampo y ncleo accumbens

131 LoquetA.El MammeriN.StanekJ.BerbonM.BardiauxB.PintacudaG.et al (2018a)

Lion's Mane mushroom - Stimulates nerve growth factor (NGF), complementing dihexa's HGF potentiation

These findings were further confirmed by treatment of HDAC6 inhibitor tubacin to PC-12 cells over-expressing human mutant (A53T) -synuclein (-syn) and SH-SY5Y cells with MPP (+) that led to defects in aggresome formation accompanied by massive cell death in response to misfolded protein-induced stress (Su et al., 2011)

Complex I is composed of 45 subunits, among which Ndufa1 is essential for complex I assembly and activation [27, 28]