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Hyperbaric oxygen therapy also has some radiosensitization effects, but it highly increases the radiation damage to normal tissues 8

2012;2012 doi: 10.1136/bcr-02-2012-5819

It functions as a cofactor for mitochondrial enzymes specifically pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase that are essential for converting glucose into cellular energy (ATP) [1][2]