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Mechanistic studies addressing anti-inflammatory and gut microbiota regulation lack depth in molecular biology and cellular signaling pathways, making it difficult to precisely delineate the synergistic actions of complex components

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Caspases are broadly classified into inflammatory caspases, such as caspase-1, -4, -5, and -11, and apoptotic caspases, such as caspase-3, -6, -7, -8, -9, and -10, reflecting their distinct but interconnected functions ( Autophagy is a cellular process in which cytoplasmic proteins or organelles are engulfed into vesicles that fuse with lysosomes to form autolysosomes, where the contents are subsequently degraded ( 3.5 Ferroptosis Iron is involved in several mechanisms of neuronal damage following ischemic stroke

Recent research has indicated that the elevated expression of the iron-regulatory protein IRP1 increases DMT1 levels and simultaneously reduces ferroportin-1 (FPN1) levels

Liquiritin apioside alleviates colonic inflammation and accompanying depression-like symptoms in colitis by gut metabolites and the balance of Th17/Treg