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doi: 10.1016/j.ajem.2020.12.062

These effects of Pycnogenol on joints can be explained by previous findings, showing that regular intake of Pycnogenol leads to a potent decrease of pro-inflammatory markers like NF-B and COX-enzymes, as well as a decline in the release of matrix metallopeptidase (MMP) enzymes, that are responsible for destroying cartilage in joints (1518, 71)

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Finally, exploring the potential for therapeutic interventions that target the aging processes within RBCs could pave the way for novel strategies to promote healthy aging and prevent age-related diseases