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Over the past few years, both human and veterinary medicine have recognized the importance of the 'One Health concept: bringing together human and animal health for new medical solutions, advantageous for humans as well as animals

Thus, these molecular imbalances redirect cellular fate from adaptive survival toward oxidative injury and programmed cell death

Unlike AMs in healthy lungs, which produce minimal NO, COPD macrophages exhibit concurrent upregulation of inducible nitric oxide synthase (iNOS) and Arg1 [83, 84]

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Pharmacological studies on sea buckthorn are also discussed