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Effects on Fibroblasts and Extracellular Matrix AHK-Cu primarily affects fibroblasts, cells responsible for maintaining and growing the extracellular matrix (ECM)[1]

To support these results, we also examined protein expression of IR and IGF-1R following CD4 + T cell activation using immunoblot and found that IR protein levels were unchanged following CD4 + T cell activation, whereas IGF-1R protein levels were indeed upregulated following activation and accumulated over time (Fig

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