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10.1155/2016/9512743 124 MashimoT.PichumaniK.VemireddyV.HatanpaaK

Figure 1 (B) Phosphorylation sites of DOR

Eventually, abundant ROS promote a series of oxidative stress reactions, such as lipid peroxidation and activation of proteases, which trigger the cell-death cascade

The core protective effects of citrulline are largely exerted through its metabolite NO, which operates via three interrelated mechanisms: first, by inhibiting the mitochondrial translocation of the fission protein Drp1, thereby preserving mitochondrial structural integrity