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Evidence linking Arctic amplification to extreme weather in mid-latitudes

World J Clin Cases 12(12):2031 Vettore LA, Westbrook RL, Tennant DA (2021) Proline metabolism and redox

We suggest that reduced GPx1 in monocytes recruited to the gut and intestinal macrophages renders these cells vulnerable to reactive oxygen species-evoked ferroptosis cell death and that unraveling the participation of this pathway in Crohns disease may reveal novel therapeutic approaches to this chronic condition