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Epitalon did increase, but not statistically significantly, the expression rates of these proteins compared to the control group [16]

It should be clarified that although the contribution of immune cells to metabolic diseases is mainly concentrated in AT, an effective source of such inflammation also exists in the liver, intestines, and other metabolic regulatory tissues, promoting the production of inflammation and obesity throughout the body through the circulation (131)

PPAR- agonists reduce collagen release, prevent fibroblast-to-myofibroblast differentiation, and inhibit key fibrogenic factors like TGF-, PDGF, and connective tissue growth factors, all of which are central to fibrotic progression [190, 191]

This is hypothesized to preserve the bodys methyl pool, which is essential for DNA methylation and epigenetic regulation

selected five traditional medicines: Ophiopogon japonicus , Lycium chinense , Senna tora , Cuscuta chinensis , and Dendrobium nobile with a potential role in enhancing ocular health and used the plant as decoction formulation in vivo study