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conducted metabolomic analysis of 17 primary glioblastoma multiforme (GBM) tumours, xenograft tumours derived from a series of GBM lines and a 50 GBM tumour metabolomic dataset, which overall showed no significant difference in MTA levels between MTAP -negative and MTAP -positive primary tumours (102)

150 as well as glycolysis, such as miR-143, miR-145 and miR-155 for hexokinase 2 (HK2), 151, 152, 153, 154, 155, 156 miR-200 for glucose-6-P isomerase (GPI), 157 miR-15a/16-1 and miR-122 for aldolase A (ALDOA), 158 miR-326 and miR133a/b for PKM2

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The reaction catalyzed by GPAT is the regulatory enzyme of the pathway

The authors resolved their disagreements through discussion