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In Mecp2-deficient mice, NTS neurons show significantly reduced amplitudes and frequencies of sIPSCs and mIPSCs, indicating impaired synaptic transmission, and decreased eIPSC amplitudes, though the paired-pulse ratio (PPR) remains unchanged, suggesting that postsynaptic mechanisms may contribute to the weakening of GABAergic inhibition

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Fragments 1 3 were thus synthesized by slightly modified reported procedures (Scheme 1) ( 1 H and 13 C NMR), which are reported in the Methods Section

It acts as a competitive inhibitor of PCFT folate transport, reducing folate entry into the brain

Progress of ginsenoside Rb1 in neurological disorders