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In conclusion, as shown in Fig S1, the activation of eNOS by BPC 157 is mediated through multiple regulation processes including the promotion of VEGFR2 activation and endocytosis, the activation of positive regulator AKT, the reduction of the interaction of negative regulator Cav-1 with eNOS

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While neurons express enzymes for glycogen synthesis, proteasome-dependent mechanisms keep neuronal glycogen synthase in an inactive state, preventing glycogen storage (Magistretti and Allaman, 2007