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Hypertension 56 , 988994 (2010)

On the one hand, the released Fe 3+ could deplete the overexpressed glutathione (GSH) through redox reactions and produce Fe 2+ , which in turn converts endogenous H 2 O 2 into highly cytotoxic hydroxyl radicals (OH) for chemodynamic therapy (CDT)

31 Acetylcysteine may be beneficial in patients presenting with acetaminophen-induced hepatic failure, as it improves hemodynamics and oxygen use, decreases cerebral edema, and improves mitochondrial energy production