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Surprisingly, we found that erastin-induced ESC ferroptosis could trigger the production of angiogenic, inflammatory, and growth cytokines, which may provide an original thinking to the positive effect of ferroptosis on the development of endometriosis

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Chronic exposure to these factors leads to sustained immune cell activation, which in turn drives mitochondrial dysfunction and elevated ROS levels further amplifying immune activation and inflammatory signaling (Kaliszewska et al., 2021