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Description

TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKvarepsilon supports the anabolic demands of dendritic cell activation

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264 It also regulates p62/SQSTM1 acetylation (K420/K435), which is critical for recognizing ubiquitinated protein aggregates, 265 and Hsp90 acetylation (K489), which enhances its interaction with LAMP-2A to promote CMA and reduce -synuclein aggregation in PD

The deletion of FSHR , LHR , or both, impedes granulosa cell survival and follicle development, ultimately altering oocyte quality through failure of cell maturation (4)