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Hypercaloric enteral nutrition in patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled phase 2 trial

10.1371/journal.pgen.1000136 PLoS Genet

However, in the phase III trial (NCT01281189) with RPPX (150 mg twice daily) in 943 people with ALS, this compound failed to show any efficacy on functional and survival assessment, when compared with placebo control (Table 2) [192]