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2d), validating their use as a genetic model for MD-related autistic-like behavior

Astrocytes indirectly promote OL survival by inducing apoptosis in CD4+ T cells 182 , and peripheral immune cells in MS produce leukaemia inhibitor factor (LIF) which protects OLs from TNF-induced death in vitro 183

It regulates the production of several hormones, including melatonin

These URIs cause and are caused by a sub optimal gut microbiome (Yildiz et al., 2018

These results suggested that chronic hypoxia promotes hyperphosphorylation of -syn through inhibition of PP2A activity and further inhibition of PP2A activity through p--syn, creating a vicious cycle