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analyze the pathomechanisms of obesity-induced chronic low-grade inflammation leading to oxidative stress, mitochondrial dysfunction, and epigenetic alterations

De la Torre [12] has calculated that postponing the onset of AD by 5 years could reduce patient numbers by upwards of 50%

Eur J Heart Fail 23(1):92113 Hambrecht R et al (1997) Effects of endurance training on mitochondrial ultrastructure and fiber type distribution in skeletal muscle of patients with stable chronic heart failure