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10.1073/pnas.96.26.14967 49 SuiX.ZhangR.LiuS.DuanT.ZhaiL.ZhangM.et al (2018)

However, if you are new to using these active ingredients, you may want to alternate their applications to minimize the chance of irritation

313 Cationic liposomes formulated with DOTAP/DSPC/cholesterol were shown to be capable of activating Toll-like receptor 4 (TLR4), inducing a greater pro-inflammatory response with enhanced Th1 cytokines expression in mice compared with ionic liposomes formulated with DSPG/HSPC/cholesterol