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Rather than assessing the overall protein adduct formation in the cell, which was initially considered to be critical for cell death20, it now appears that protein adduct formation on mitochondrial proteins is most relevant for toxicity2123

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Recovery two years after brain injury Based on information of people with moderate to severe TBI who received acute medical care and inpatient rehabilitation services at a TBI Model System, two years post-injury: Most people continue to show decreases in disability

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