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In the general population, vitamin B12 deficiency affects: About 3% of people aged 20 to 40 Up to 20% of those aged 85 and older However, studies suggest that 30% to 50% of individuals who have undergone surgeries involving the removal of the terminal ileum or colon may develop B12 deficiency, up to 15 times higher than the general population

In a systematic review, researchers found inadequate evidence to determine if intravenous vitamin C was beneficial for cancer treatment

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Published studies in rodent models have documented effects on tendon-to-bone healing, ligament recovery, muscle crush injury recovery, and gastrointestinal mucosal integrity