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Azumamides A-E: histone deacetylase inhibitory cyclic tetrapeptides from the marine sponge Mycale izuensis

1 Introduction Thyroid-associated ophthalmopathy (TAO), also known as Graves ophthalmopathy, is an autoimmune condition affecting the eyes, orbit, and surrounding structures ( Despite the intricate interplay of genetic, environmental, and immune factors, the exact mechanisms underlying TAO remain incompletely understood ( Oxidative stress contributes to TAO through multiple mechanisms

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N Engl J

Gurel, The effects of ferulic acid against oxidative stress and inflammation in formaldehyde-induced hepatotoxicity