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Cerebrovascular accidents in sickle cell disease: rates and risk factors

While glycolysis in the cytosol also produces some ATP, mitochondria are the primary source

The standard treatment includes surgery and platinum-based chemotherapy, but there has been increasing use of anti-angiogenic Bevacizumab and Poly(ADP-ribose) polymerase (PARP) inhibitors in the past decade [296]

Moreover, their prototypic inhibitor cyclosporine A (CsA) causes an oxidative shift in cellular glutathione, presumably by increasing the oxidation state of the ER [49]