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LDN has the ability to reduce pro-inflammatory cytokines as it was found to be allied with a decline of plasma concentrations of transforming growth factor (TGF)- which belongs to a group of cytokines that is together called The super-family TGF-, and also responsible for regulating epithelial cell differentiation, expansion , organization, motility, and apoptosis [98]

It works by reducing the appearance of pigmentation, dark spots, and uneven skin tone

The area under the blood concentration-time curve (AUC) is proportional to the dose and the extent of bioavailability for a drug if its elimination is first-order ( Figure 34 )

These changes tend to be progressive, not overnight, which fits the clinic's focus on sustainable, science-based results

The application of new drug delivery technologies to Chinese herbal medicines will undoubtedly help to enhance the therapeutic efficacy of various Chinese medicinal compounds and herbs while reducing the side effects of drugs