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Pickart published 46 articles in peer-reviewed scientific journals and held 29 patents

It is predominantly known for its skin-brightening properties

According to the FDA's press release it agreed to approve the drug for obesity based on three randomised, double-blind, placebo-controlled trials during which more than 2,600 patients received Wegovy for up to 68 weeks and more than 1,500 patients received placebo (US FDA 2021)

Immune tolerance mechanisms, including central tolerance in the thymus and peripheral tolerance in secondary lymphoid organs, are essential for preventing autoimmunity [139, 140]