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10.1038/nrd4002 58 HammadS

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In an animal model, NAC increased lung cancer cell proliferation due to its antioxidant activity by reducing ROS, DNA damage, and p53 expression (36)

To study the permeability of nanoparticles in vitro BBB models, which conform to the 3R principles with the minimalization the number of animal experiments, are widely used either in static [34] or in dynamic conditions by employing lab-on-a-chip systems [35]

M., Reddy, V., & Pillarisetty, L