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However, this process is significantly impaired in the obese state

Depending on how short (or how long) the t1 time is, the signal amplitude observed at t2 will vary

However, better delineation of the therapeutic and prophylactic roles of L-carnitine in these conditions will require further investigations in controlled, randomized and probably multicentre trials to evaluate the clinical value and the appropriate dosage of L-carnitine in each of these conditions

10.3390/ijms24032749 113 LiH.WangX.MuH.MeiQ.LiuY.MinZ.et al (2022a)

Kumar S, Lee JH, Lahuerta JJ, Morgan GJ, Richardson PG, Crowley J, Haessler J, Feather J, Hoering A, Moreau P, Leleu X, Hullin C, Klein SK, Sonneveld P, Siegel DS, Blad J, Goldschmidt H, Jagannath S, San Miguel JF, Orlowski RZ , Palumbo A, Sezer O, Rajkumar SV, and Durie BGM