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The hydroxylation of proline by prolyl hydroxylase (or other additions of electron-withdrawing substituents such as fluorine) increases the conformational stability of collagen significantly

Comorbidity of epilepsy and depression: associated pathophysiology and management

doi: 10.1016/j.cmet.2018.08.004

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64, 65 Some findings strongly indicate that ROS in the rostral ventrolateral medulla is increased in stroke-prone spontaneously hypertensive rats and thereby contributes to the neural mechanisms of hypertension through activation of the sympathetic nervous system