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When overexpressed, ACADSB, a member of the acyl-CoA dehydrogenase, that negatively regulates glutathione reductase and GPX4, was shown to limit CRC cell migration, invasion, and proliferation by promoting CRC cell ferroptosis [151]

doi: 10.1046/j.1471-4159.2003.01854.x

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Additionally, the role of appendix diameter, as measured by imaging modalities, warrants further investigation in larger, diverse populations to confirm its predictive value