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[Abstract]2026 Feb 13;12(2):623-636

It is important to realize that patients with baseline functional anemia (e.g., sickle cell anemia or carboxyhemoglobinemia) will become symptomatic at lower methemoglobin fractions [1]

In terms of anti-inflammatory effects, folic acid suppresses the activation of the NF-B pathway induced by ROS and Hcy, thereby downregulating the expression and secretion of pro-inflammatory cytokines such as TNF- , IL-6, and IL-1 (67)

78 Chronic liver inflammation disrupts protein and amino acid metabolism, increasing ammonia and GGT levels

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