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Our study did not find that GGT plays a mediating role in the relationship between OBS and diarrhea, but oxidative stress cannot be considered to play a role in the relationship between OBS and diarrhea, as other biomarkers that respond to oxidative stress, such as F2 isoproteins, were not included in this study due to incomplete data information in the NHANES database

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The expression of CD44 on CD4 + T-cells is known to promote the occurrence of type 1 helper (Th1) responses and the generation of inflammatory cytokines ( + DCs, which were characterized by the expression of co-stimulative markers CD80 and CD86 ( + Treg cells is crucial for maintaining intestinal immune tolerance ( Figure 2E )