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Even though multiple in vitro, in vivo, and clinical studies reveal that glutamine has an advantageous function in the maintenance of the mucosal barrier, larger randomized trials are required to evaluate the advantageous effects of glutamine

Consistent with this, a recent study demonstrated that catabolism of extracellular glutathione can supply cysteine to support tumor growth under cystine-limited conditions 150

51 NovinscakT.BrcicL.StaresinicM.JukicI.RadicB.PevecD.et al (2008)

In a different study, the impact of methotrexate was evaluated in a Swiss mouse skin tumor model methylcholanthrene (MCA)

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