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Abiotic stress adaptation in plants: physiological, molecular and genomic foundation

2020, Feb, 3;10(1):52 Almeida FM, Battochio AS, Napoli JP, Alves KA, Balbin GS, Oliveira-Junior M, et al

However, the research in this area is still inconclusive

On the one hand, cancer metabolism-related signals or metabolites affect the activation and function of microenvironmental antitumor immune cells (T cells and NK cells) in the TME, and on the other hand, cancer-associated stromal cells, such as CAFs, and immunosuppressive cells (M2 macrophages and MDSCs) reshape the local metabolic environment and oncogenic pathways, further promoting malignant tumor progression