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For instance, lactylation at K503 of lysine-specific demethylase 1 (LSD1) enhances the formation of a stable complex with transcription factor FosL1, specifically enriching at the ferroportin receptor TFRC promoter region to suppress TFRC transcription, reduce iron uptake and enhance ferroptosis resistance (79)

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TMA to TMAO Kinetics: Once anaerobic bacteria harboring ET hydrolases cleave the molecule into volatile trimethylamine (TMA), the gas is rapidly absorbed via portal circulation

Purcell SH, Chi MM, Lanzendorf S, Moley KH