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Description

Such dynamic changes in putative biomarkers is a well-established aspect of schizophrenia (Figure 2 where this scenario is described as Adaptive GSH Changes. Figure 2 (B) In this model, GSH changes are considered to be adaptive consequences of glutamatergic aberrations

They increase oxidative stress and slow pigment cell activity

Med 10 , 5857 (2021)

doi: 10.1038/nm.4262

[58] have shown that Nrf2 deficiency leads to oxidative stress and DNA lesions, accompanied by impairment of cell-cycle progression, mainly G(2)/M-phase arrest