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They are particularly beneficial for individuals with absorption issues, long-term fatigue, anaemia, or medically confirmed deficiency

Thus, in pregnancy serum holoTC offers a diagnostic advantage over total serum B12 (Varsi et al., 2018)

He was able to give resistance with flexion and extension at the knees, and there was slight bilateral ankle dorsiflexion noted

This makes supplements more similar to the natural kind of B12 in foods and a combination of methylcobalamin, adenosylcobalamin and hydroxocobalamin is considered ideal