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Journal of the Canadian Academy of Child and Adolescent Psychiatry, 21 (3), 223-229

For some, that decline may not cause obvious issues

Future trials should enrich truly deficient, higher-risk phenotypes, standardize regimens, and prioritize event-driven hard endpoints with embedded mechanistic markers to confirm on-target biology

40 Jing F, Zhu L, Zhang J, Zhou X, Bai J, Li X, Zhang H, Li T

Following incubation and washing, TMB substrate solution is then used to visualize the HRP enzymatic reaction by catalysis to produce a blue-coloured product that changes to yellow after addition of acidic stop solution