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Pragmatic constraints precluded measurement of water and metabolite T1 and T2 relaxation times in individual subjects

Considering the lack of standardised approach for deriving dietary recommendations for B-vitamin intakes in pregnancy, and the fact that most existing recommendations are based on extrapolation from values for non-pregnant women and estimated needs for tissue growth and fetal transfer, there is a need for well-designed controlled feeding trials to be conducted in pregnancy

Site rotation schedule Rotating injection sites prevents lipohypertrophy, a condition where repeated injections cause fatty tissue changes

Even if absorption weren't an issue

The required dose is 20 to 40 mg (milligram) per kg body weight of 1 g (gram) to 2 g per day in two divided doses