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Upon comparing the glioblastoma (GBM) high- and low-expression groups for MDM2, the high-expression group was found to be approximately 50-fold more sensitive to RSL3-induced ferroptosis in cancer cells than the MDM2 low-expression group

Liu Y, Song Z, Liu Y, Ma X, Wang W, Ke Y, et al

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NMR Biomed 34(5):132

Figure 1: Kaplan-Meier Curve for Overall Survival in KEYNOTE-189* *Based on the protocol-specified final OS analysis Initial Treatment in Combination with Cisplatin The efficacy of pemetrexed was evaluated in Study JMDB (NCT00087711), a multi-center, randomized (1:1), open-label study conducted in 1725 chemotherapy-naive patients with Stage IIIb/IV NSCLC