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References: Wang C, Crapo LM (1997) The epidemiology of thyroid disease and implications for screening

Cherbut C

Lastly, while APOE effects dominated brain profiles, sex effects were more prominent in the periphery, which was also in accordance with a previous study in older (16 months old) APOE-TR mice (Shang et al., 2020), suggesting that regardless of age APOE has a major effect on brain bioenergetics